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s deeper and the discharge copious and often offensive; the scarring is soft, and, compared to the amount of ulceration, but slightly disfiguring; and it is, for obvious reasons, a disease of adult or late life. The history, together with other evidences of previous or concomitant symptoms of syphilis, will often aid in the differentiation. #How does epithelioma differ from lupus vulgaris?# The edges of the epitheliomatous ulcer are hard, elevated and waxy; the base is uneven, the secretion thin, scanty and apt to be streaked with blood; the ulceration usually starts from one point, and is often painful; the tissue destruction may be considerable; there is little, if any, tendency to the formation of cicatricial tissue; and, finally, it is usually a disease of advanced age. #In what respects does lupus erythematosus differ from lupus vulgaris?# Lupus erythematosus has no papules, tubercles or ulceration. #How does acne rosacea differ from lupus vulgaris?# Acne rosacea is characterized by hyperaemia, dilated vessels, papules, pustules, the absence of ulceration, and a different history. #State the prognosis of lupus vulgaris.# Lupus vulgaris is always a chronic disease, often exceedingly rebellious to treatment, and one that calls for a guarded opinion. Relapses are not uncommon. [Illustration: Fig. 46. Galvano-cautery Needle, Knife and Spiral Points. (_As devised by Besnier._)] The general health usually remains good, but in some instances death by tuberculosis of the lungs has been noted. #Is external or internal treatment called for in lupus vulgaris?# Always external, and not infrequently constitutional also. #What is the constitutional treatment?# The general health must be cared for; good, nutritious food, fresh air and out-door exercise, together with, in many cases, the administration of such remedies as cod-liver oil, potassium iodide, iron and quinine, are of therapeutic importance. Tuberculin may be tried in severe and obstinate cases, but its use is not without danger. #State the object of local treatment.# The destruction or removal of the diseased tissue. #May milder methods of treatment sometimes prove beneficial and even curative?# Exceptionally, mercurial plaster, corrosive-sublimate lotion and ointment (gr. j to [Oz]j), a plaster containing five to fifteen per cent. of salicylic acid and creasote, repeated paintings with carbolic acid, and the
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