ler daily dose for another two or three months;
and so on, for a period of at least two years.
(Almost all authorities are agreed as to the importance of prolonged
treatment, but differ somewhat on the question of intermittent or
uninterrupted administration.)
#Give the constitutional treatment of the late, or localized,
syphilodermata.#
Mercury always, usually in small or moderate dosage, as the biniodide or
corrosive chloride, and potassium iodide; the latter in dose varying
from two grains to two drachms or more, t.d., depending upon its action
and the urgency of the case.
#How long is constitutional treatment to be continued in cases of the
late syphilodermata?#
Actively for several weeks after the disappearance of all symptoms, and
then (especially the mercury) continued in smaller dosage (about
one-third) for several months longer.
#What applications are usually advised in the late, or localized,
syphilodermata?#
Ointment of ammoniated mercury, twenty to sixty grains to the ounce;
oleate of mercury, five to ten per cent. strength; mercurial plaster,
full strength or weakened with lard or petrolatum; a two to twenty per
cent. ointment of iodol; resorcin, twenty to sixty grains to the ounce
of ointment base; and lotions of corrosive sublimate, one-half to three
grains to the ounce.
The following is valuable in offensive and obstinate ulcerations:--
[Rx] Hydrarg. chlorid. corros., ........... gr. iv-gr. viij
Ac. carbolici, ....................... gr. x-xx
Alcoholis, ........................... f[dram]iv
Glycerinae, ........................... f[dram]j
Aquae, ............ q.s. ad ........... [Oz]iv. M.
Ointments are to be rubbed in or applied as a plaster; lotions, employed
chiefly in ulcers and ulcerations, are to be thoroughly dabbed on, and
usually supplemented by the application of an ointment. Iodol may also be
applied to ulcers as a dusting-powder, usually mixed with one to several
parts of zinc oxide or boric acid.
#Give the treatment of hereditary infantile syphilis.#
It is essentially the same (but much smaller dosage) as employed in
acquired syphilis. Attention to proper feeding and hygiene is of first
importance.
Mercury may be given by the mouth, as mercury with chalk (gr. ss-gr. ij,
t.d.); as calomel (gr. 1/20-gr. 1/6, t.d.); and as a solution of
corrosive sublimate (gr. ss-[Oz]vj, [dram]j, t.d.). If mercury is not
well borne by th
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