e, in particular for the question of transitory
hyperleucocytosis, which is by some referred to a destruction, by others
to an altered localisation of the white blood corpuscles.
4. "=Stimulation forms=" were first described by Tuerk, and are mononuclear
non-granulated cells. They possess a protoplasm staining with various
degrees of intensity, but in any case giving with triacid solution an
extraordinarily deep dark-brown, and further a round simple nucleus
often eccentrically situated, stained a moderately deep bluish-green,
with however a distinct chromatin network. The smallest forms stand
between the lymphocytes and the large mononuclear leucocytes, but
approach the first named as a whole in their size and general
appearance. According to Tuerk's investigations, these cells often occur
simultaneously with, and under the same conditions as the myelocytes.
Their importance cannot at present be accurately gauged. Possibly they
form an early stage of development of the nucleated red blood
corpuscles, as the deeply staining and homogeneous protoplasm seems to
indicate.
With the description of these abnormal forms of white corpuscles all
occurring forms are by no means exhausted. We are here excepting
completely the variations in size which particularly affect the
polynuclear and eosinophil cells, and which lead to dwarf and giant
forms of them. For however considerable the difference in size, these
cells always possess characteristics sufficient for an exact diagnosis.
But besides these, isolated cells of an especially large kind are found
particularly in leukaemic blood, and concerning their importance and
relationship we are up to the present in the dark.
FOOTNOTES:
[11] In enumerating the blood corpuscles, 2 and 3 may be counted
separately or in one group.
[12] The assumption of Czerny, that the cells which react to iodine
emigrate from suppurating foci, is without foundation. A simple
investigation of freshly inflamed tissue is sufficient to show that the
cells which have wandered from the blood stream soon contain glycogen.
[13] Kanthack described this group as "finely granular oxyphil" cells.
Their granules stain red in eosine and in eosine-methylene blue
solutions, but the colour is different from that of the true eosinophil
cells, and much less intense. In the latter mixture they stain really
with the methylene blue salt of eosine. Their true nature is shown by
their behaviour with the triacid solut
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