sine-aurantia-nigrosin mixtures. One principal distinction
between these two forms of cells lies in the fact that,
according to Kurloff, this granulation is very easily dissolved
by acid, but remains unchanged in alkaline solutions; doubtless
an indication that the granulation consists of a basic body
soluble with difficulty, which with acids forms soluble salts.
The true eosinophil granulation remains, on the other hand,
quite unchanged under these conditions.

=These pseudoeosinophil, polynuclear cells, correspond
functionally to the neutrophil polynuclear of man=; their number
amounts to 40-50% of the total white cells. The red bone-marrow
is to be regarded as the place of origin of this kind of cell.
It contains very many pseudoeosinophil cells, and indeed all
stages are to be found in it, from the mononuclear cells
bearing granules to the fully formed polynuclear.

2. The typical =eosinophil leucocytes=, which fully correspond to
those found in man, and amount to about 10% of the number of
the white.

3. The "=nigrosinophil cells=," as they are called by Kurloff. In
their general appearance, in the size of the cell and the
granulation, they completely correspond to the eosinophil cell.
The only distinction between them consists in a chemical
difference in the granulation. These cells stain in the colour
of nigrosin in the aurantia-eosin-nigrosin mixture, whilst the
eosinophil cells become red. The two granulations always show
different shades in the triacid preparation as well; for the
nigrosinophil cells stain a blacker hue.

II. Cells free from granules.

([alpha]) Cells with vacuoles.

This is a quite peculiar group, characteristic for the blood of
the guinea-pig. It shews transitions in the blood, from large
mononuclear to transitional and polynuclear forms, but is
marked by the lack of any kind of granulation. Instead of the
latter, we find in these cells a roundish, nucleus-like form in
the protoplasm, which also takes the nuclear stains, and
possibly is to be considered an accessory nucleus. We have
received the impression that we have here to deal with a
vacuole filled with substance secreted by the cell. In a large
series of preparations, it is possible to obtain some
elucidation of the development and fa