ibed. We
made counts in oldish and fresh preparations. It is worthy of
notice that this case is not uncomplicated, as an amputation of
the thigh was performed shortly after the splenectomy on
account of gangrene.

We found the following figures.

------------------------------------------------------------------------
Preparations from | Polynuclear | Lymphocytes | Eosinophil | Large
| | | | mononuclear
------------------------------------------------------------------------
June 12, 1892 | 81.9% | 15.9% | 1.3% | --
October 11, 1892 | 80.0% | 13.7% | 4.0% | 1.7%
September, 1897 | 56.8% | 33.1% | 3.5% | 1.5%
------------------------------------------------------------------------

It is much to be regretted that dry preparations only at the beginning
and at the end of the five year period of observation were at our
disposal. It appears from the paper of Riequer as if in this case the
lymphocytosis had established itself one month after the operation, and
had lasted for a very long time, just as Kurloff has found in some
animal experiments. Just as little as a polynuclear increase is
abnormal, is an increase of the lymphocytes remarkable; and in this case
the lymphocytic increase was recognisable after the end of the fifth
year. The eosinophil cells oscillate at this period about the upper
normal limit. From all that we know, it is probable that their number in
the meantime had undergone an intercurrent increase.

The cases are more frequent in which a splenectomy has been undertaken
on account of disease of the spleen. Amongst these, the clearest results
are _a priori_ to be expected from splenic cysts, since the part of the
spleen not affected by the cyst formation often shews quite a normal
structure, and therefore is physiologically active. On the other hand,
the excision of chronic splenic tumours may be--for the blood
condition--of no importance inasmuch as the function of the spleen may
have previously long been eliminated by pathological changes.

Amongst these cases, we must in the first place mention the well-known
and carefully investigated case of B. Crede. In a man 44 years of age
the spleen was extirpated on account of a large splenic cyst. Within two
months of the operation there developed a thoroughly leukaemic condition
of the blood, exclusively brought a