nter.

A very careful consideration was given to possible sites in a number of
cities, with the result that the laboratory was constructed on a plot of
ground in Boston in the vicinity of large hospitals and medical schools.
Advantage was taken, also, of the opportunity to secure connections with
a central power-plant for obtaining heat, light, electricity, and
refrigeration, thus doing away with the necessity for private
installation of boilers and electrical and refrigerating machinery. The
library advantages in a large city were also of importance and within a
few minutes' walk of the present location are found most of the large
libraries of Boston, particularly the medical libraries and the
libraries of the medical schools.

The building, a general description of which appeared in the Year Book
of the Carnegie Institution of Washington for 1908, is of plain brick
construction, trimmed with Bedford limestone. It consists of three
stories and basement and practically all the space can be used for
scientific work. Details of construction may be had by reference to the
original description of the building. It is necessary here only to state
that the special feature of the new building with which this report is
concerned is the calorimeter laboratory, which occupies nearly half of
the first floor on the northern end of the building.

FOOTNOTES:

[1] Pettenkofer and Voit: Ann. der Chem. u. Pharm. (1862-3), Supp. Bd.
2, p. 17.

[2] Atwater, Woods, and Benedict: Report of preliminary investigations
on the metabolism of nitrogen and carbon in the human organism with a
respiration calorimeter of special construction, U. S. Dept. of Agr.,
Office of Experiment Stations Bulletin 44. (1897.)

[3] W. O. Atwater and F. G. Benedict: A respiration calorimeter with
appliances for the direct determination of oxygen. Carnegie Institution
of Washington Publication No. 42. (1905.)

CALORIMETER LABORATORY.

The laboratory room is entered from the main hall by a double door. The
room is 14.2 meters long by 10.1 meters wide, and is lighted on three
sides by 7 windows. Since the room faces the north, the temperature
conditions are much more satisfactory than could be obtained with any
other exposure. In constructing the building the use of columns in this
room was avoided, as they would interfere seriously with the
construction of the calorimeters and accessory apparatus. Pending the
completion of the five calorimeters desig