gature or by the galvano-cautery.

#Neuroma.#

#Describe neuroma.#

Neuroma of the skin is an exceedingly rare disease, characterized by the
formation of variously-sized, usually numerous, firm, immovable and
elastic fibrous tubercles containing new nerve-elements, and accompanied
by violent, paroxysmal pain. Their growth is slow and usually
progressive. Later they are painful upon pressure. They are limited to
one region.

The tumors are seated in the corium, extending into the deeper
structure, and consist of nerve-fibres, yellow elastic tissue, blood
vessels and lymphoid cells.

In the two cases reported, excision of the nerve-trunk gave, in one
instance, permanent relief; in the other the effect was only temporary.

#Xanthoma.#
(_Synonyms:_ Vitiligoidea; Xanthelasma.)

#What is xanthoma?#

Xanthoma is a connective-tissue new growth characterized by the
formation of yellowish, circumscribed, irregularly-shaped,
variously-sized, non-indurated, flat or raised patches or tubercles.

#Name the two varieties met with.#

The macular or flat (_xanthoma planum_) and the tubercular (_xanthoma
tuberculatum_ or _tuberosum_). In some instances both varieties
(_xanthoma multiplex_) are seen in the same individual.

#Describe the clinical appearances of xanthoma planum.#

The macular or flat variety is usually seen about the eyelids. It
consists of one, several or more small or large, smooth, opaque,
sharply-defined, often slightly raised, yellowish patches, looking not
unlike pieces of chamois-skin implanted in the skin.

#Describe the clinical appearances of xanthoma tuberosum.#

The tubercular variety is commonly met with upon the neck, trunk and
extremities. It occurs as small, raised, isolated, yellowish nodules, or
as patches made up of aggregations of millet-seed-sized or larger
tubercles. The lesions may be few or they may exist in great numbers.

#What is the course of xanthoma?#

Extremely slow; after reaching a certain development the growths may
remain stationary.

#State the etiology of xanthoma.#

The causes are obscure. Jaundice not infrequently precedes and
accompanies its development, especially in the tubercular variety. The
disease is uncommon, and is usually seen in middle and advanced life,
and more frequently in women. In some cases (_xanthoma diabeticorum_) of
general xanthoma diabetes is