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e safely in solution, and these are liable to crystallize out and form stone and gravel. Similarly the passage, in the sweat, of some of the solids that normally leave the body, dissolved in the urine, serves to irritate the skin and produce troublesome eruptions. PROMINENT CAUSES OF URINARY DISORDERS. A disordered liver contributes to the production under different circumstances of an excess of biliary coloring matter which stains the urine; of an excess of hippuric acid and allied products which, being less soluble than urea (the normal product of tissue change), favor the formation of stone, of taurocholic acid, and other bodies that tend when in excess to destroy the blood globules and to cause irritation of the kidneys by the resulting hemoglobin excreted in the urine, and of glycogen too abundant to be burned up in the system, which induces saccharine urine (diabetes). Any disorder leading to impaired functional activity of the lungs is causative of an excess of hippuric acid and allied bodies, of oxalic acid, of sugar, etc., in the urine, which irritate the kidneys, even if they do not produce solid deposits in the urinary passages. Diseases of the nervous system, and notably of the base of the brain and of the spinal cord, induce various urinary disorders, prominent among which are diabetes, chylous urine, and albuminuria. Certain affections, with imperfect nutrition or destructive waste of the bony tissues, tend to charge the urine with phosphates of lime and magnesia and endanger the formation of stone and gravel. In all extensive inflammations and acute fevers the liquids of the urine are diminished, while the solids (waste products), which should form the urinary secretion, are increased, and the surcharged urine proves irritant to the urinary organs or the retained waste products poison the system at large. Diseases of the heart and lungs, by interfering with the free, onward flow of the blood from the right side of the heart, tend to throw that liquid back on the veins, and this backward pressure of venous blood strongly tends to disorders of the kidneys. Certain poisons taken with the feed and water, notably that found in magnesian limestone and those found in irritant, diuretic plants, are especially injurious to the kidneys, as are also various cryptogams, whether in musty hay or oats. The kidneys may be irritated by feeding green vegetables covered with hoar frost or by furnishing an excess of
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