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morning and ending after the first specimen has been voided on the morning of the second day. ~Preserving the Urine~ for testing is usually necessary, especially during the warm weather. The specimens should be collected in a wide-mouthed sterile glass jar. This should be kept in a cold place. Some harmless preservative such as chloroform should be added to assure its keeping. PROBLEMS (a) Outline tests used in urinalysis; state when they are used. (b) List the equipment needed for making the simple tests. (c) Make tests in laboratory and list results in note-book. FOOTNOTES: [110] "Treatment of Diabetes Mellitus," pp. 182-183, by Joslin. [111] "Starvation (Allen) Treatment for Diabetes Mellitus," by Hill and Eckman. [112] "Treatment of Diabetes Mellitus," p. 186, by Joslin. [113] "Chemistry for Nurses," by Reuben Ottenburg. CHAPTER XVIII ACUTE AND CHRONIC NEPHRITIS Nephritis is a disease of the kidneys, in which changes occur in the tissues of the organs themselves; these changes may be caused by inflammation of the kidneys and renal passages brought on as results of the retention of certain poisonous substances in the blood, or from the action of specific bacteria. The disease may be acute or chronic in form and develop as a result of prolonged exposure to cold and wet, of tonsillitis, scarlet fever, typhoid fever, and to a less extent of malaria, syphilis, pregnancy, and tuberculosis, as well as from the effects of certain irritating drugs, such as cantharides and turpentine. ~Directing the Treatment.~--In any case the treatment must be directed toward the relief of the acute symptoms in the beginning and followed up by a general treatment which will tend to strengthen and relieve the overtaxed organs and to increase their power to functionate normally. ~Causes and Effects.~--In acute nephritis, the chief symptoms are uremia, and edema; the urine is materially diminished in quantity and at times suppressed; it is often found to be rich in albumen and containing hyaline and blood casts, red and white blood cells, and various pigments. In chronic nephritis, which may be the result of an acute attack, or as a sequel of other diseases already mentioned, there is seen to be a progressive loss of flesh and strength, marked anemia, gastro-intestinal disturbances, increased blood tension and edema, the latter especially in the face on arising in the morning. Uremia may deve
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