the eyes;
these can be touched with the fingers, without causing a closing of the
lids.

The sense of _hearing_ seems to continue its functions until very late.
Children show that they hear as long as they are not completely
unconscious; even when addressed in a low tone of voice they react
somewhat. The sense of _smell and taste_ also are lost toward the very
end of the disease.

_Paralytic_ affections appear during the final stages. It has been
observed in some cases that the arm and limb are paralyzed on one side
only. Often one upper eyelid is paralyzed and hangs down on one side of
the face and the muscles of the tongue may be affected.

Generally the patient dies after violent general convulsions that last
for hours. Exceptionally only the paralytic symptoms increase gradually
and cause death without any agony or struggle, simply a discontinuance
of the functions constituting life.

The duration of the disease varies from 2-4 weeks from the beginning of
the characteristic symptoms. Generally the day when the children take to
the bed is fixed as the beginning of the disease.

The former methods of treatment have been a signal and absolute failure
in every case. Every child that has once been attacked with this disease
has heretofore died. Until now Koch has not been able to make any
experiments with acute hydrocephalus, so that it remains an open
question whether it is now possible to cure this disease.

Besides tuberculosis of the cerebral membranes with which children are
afflicted, _tuberculosis of the brain_ may occur, although this disease
is very rare. Tuberculosis of the brain appears in the shape of small
tumors in all parts of the brain. After longer duration of tuberculosis
of the brain, tubercular meningitis appears.

The process of this disease may be varied. In some cases the development
of cerebral tuberculosis is manifested by the sudden appearance of high
fever temperatures or violent headache; to this may be added,
slackening of the pulse, vomiting, stiff neck and isolated cases of
palsy; sometimes an attack of convulsions is the first manifestation.

In other cases the beginning can not be accurately determined, as the
beginning symptoms of the disease are so slight as to escape notice.
Impaired process of nutrition, languor and headache are symptoms from
which the existence of some serious affliction may be inferred without
being able to determine its nature in the earlier stages.

Aga