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the world as Anatomical Engravings, they showed conclusively that Eustachius was equal, if not superior to Vesalius in his knowledge of anatomy. It has been said of this remarkable collection of engravings that if they had been published when they were made in the sixteenth century, anatomy would have been advanced by at least two centuries. But be this as it may, they certainly show that their author was a most careful dissector and observer. Eustachius described accurately for the first time certain structures of the middle ear, and rediscovered the tube leading from the ear to the throat that bears his name. He also made careful studies of the teeth and the phenomena of first and second dentition. He was not baffled by the minuteness of structures and where he was unable to study them with the naked eye he used glasses for the purpose, and resorted to macerations and injections for the study of certain complicated structures. But while the fruit of his pen and pencil were lost for more than a century after his death, the effects of his teachings were not; and his two pupils, Fallopius and Columbus, are almost as well known to-day as their illustrious teacher. Columbus (1490-1559) did much in correcting the mistakes made in the anatomy of the bones as described by Vesalius. He also added much to the science by giving correct accounts of the shape and cavities of the heart, and made many other discoveries of minor importance. Fallopius (1523-1562) added considerably to the general knowledge of anatomy, made several discoveries in the anatomy of the ear, and also several organs in the abdominal cavity. At this time a most vitally important controversy was in progress as to whether or not the veins of the bodies were supplied with valves, many anatomists being unable to find them. Etienne had first described these structures, and Vesalius had confirmed his observations. It would seem as if there could be no difficulty in settling the question as to the fact of such valves being present in the vessels, for the demonstration is so simple that it is now made daily by medical students in all physiological laboratories and dissecting-rooms. But many of the great anatomists of the sixteenth century were unable to make this demonstration, even when it had been brought to their attention by such an authority as Vesalius. Fallopius, writing to Vesalius on the subject in 1562, declared that he was unable to find such valves. Ot
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