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with a single specimen, as, for example, Johannes Muller did half a century ago with the one available specimen of amphioxus, the lowest of vertebrates, then recently discovered. What Muller learned from that one specimen seems almost miraculous. But what if he had had a bucketful of the little boneless creatures at his disposal, as the worker at Naples now may have any day for the asking? When it comes to problems of development, of heredity, a profusion of material is almost a necessity. But here the creatures of the sea respond to the call with amazing proficiency. Most of them are, of course, oviparous, and it is quite the rule for them to deposit their eggs by hundreds of thousands, by millions even. Everybody knows, since Darwin taught us, that the average number of offspring of any given species of animal or plant bears an inverse proportion to the liability of that species to juvenile fatalities. When, therefore, we find a fish or a lobster or other pelagic creature depositing innumerable eggs, we may feel perfectly sure that the vast majority of the eggs themselves, or the callow creatures that come out of them, will furnish food for their neighbors at an early day. It is an unkind world into which the resident of the deep is born. But his adversity is his human contemporary's gain, and the biologist will hardly be blamed, even by the most tender-hearted anti-vivisectionist, for availing himself freely of material which otherwise would probably serve no better purpose than to appease the appetite of some rapacious fish. Their abundance is not the only merit, however, of the eggs of pelagic creatures, in the eyes of the biologist. By equal good-fortune it chances that colorless things are at a premium in the sea, since to escape the eye of your enemy is a prime consideration. So the eggs in question are usually transparent, and thus, shielded from the vision of marine enemies, are beautifully adapted for the observation of the biologist. As a final merit, they are mostly of convenient size for manipulation under the microscope. For many reasons, then, the marine egg offers incomparable advantages to the student of cell life, an egg being the typical cell. And since nowadays the cell is the very focus of attention in the biological world, the importance of marine laboratories has been enhanced proportionately. But of course not all the work can be done with eggs or with living specimens of any kind. It is e
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