e morbid matter from
the horse on the nipple of the cow, and passed through that medium to
the human subject.

Mr. ABRAHAM RIDDIFORD, a Farmer at Stone in this parish, in
consequence of dressing a mare that had sore heels, was affected with
very painful sores in both his hands, tumours in each axilla, and
severe and general indisposition. A Surgeon in the neighbourhood
attended him, who, knowing the similarity between the appearance of
the sores upon his hands and those produced by the Cow Pox, and being
acquainted also with the effects of that disease on the human
constitution, assured him that he never need to fear the infection of
the Small Pox; but this assertion proved fallacious, for, on being
exposed to the infection upwards of twenty years afterwards, he
caught the disease, which took its regular course in a very mild way.
There certainly was a difference perceptible, although it is not easy
to describe it, in the general appearance of the pustules from that
which we commonly see. Other practitioners, who visited the patient
at my request, agreed with me in this point, though there was no room
left for suspicion as to the reality of the disease, as I inoculated
some of his family from the pustules, who had the Small Pox, with its
usual appearances, in consequence.

_CASE XVI._

SARAH NELMES, a dairymaid at a Farmer's near this place, was infected
with the Cow Pox from her master's cows in May, 1796. She received
the infection on a part of the hand which had been previously in a
slight degree injured by a scratch from a thorn. A large pustulous
sore and the usual symptoms accompanying the disease were produced in
consequence. The pustule was so expressive of the true character of
the Cow Pox, as it commonly appears upon the hand, that I have given
a representation of it in the annexed plate. The two small pustules
on the wrists arose also from the application of the virus to some
minute abrasions of the cuticle, but the livid tint, if they ever had
any, was not conspicuous at the time I saw the patient. The pustule
on the fore finger shews the disease in an earlier stage. It did not
actually appear on the hand of this young woman, but was taken from
that of another, and is annexed for the purpose of representing the
malady after it has newly appeared.

_CASE XVII._

The more accurately to observe the progress of the infection, I
selected a healthy boy, about eight years old, for the purpose