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in Germany. Had space allowed, it would have given me pleasure to point out the present position of the 'germ theory' in reference to the phenomena of infectious disease, distinguishing arguments based on analogy--which, however, are terribly strong--from those based on actual observation. I should have liked to follow up the account I have already given [Footnote: 'Fortnightly Review,' November 1876, see article 'Fermentation.'] of the truly excellent researches of a young and an unknown German physician named Koch, on splenic fever, by an account of what Pasteur has recently done with reference to the same subject. Here we have before us a living _contagium_ of the most deadly power, which we can follow from the beginning to the end of its life cycle. [Footnote: Dallinger and Drysdale had previously shown what skill and patience can accomplish, by their admirable observations on the life history of the monads.] We find it in the blood or spleen of a smitten animal in the state say of short motionless rods. When these rods are placed in a nutritive liquid on the warm stage of the microscope, we soon see them lengthening into filaments which lie, in some cases, side by side, forming in others graceful loops, or becoming coiled into knots of a complexity not to be unravelled. We finally see those filaments resolving themselves into innumerable spores, each with death potentially housed within it, yet not to be distinguished microscopically from the harmless germs of Bacillus subtilis. The bacterium of splenic fever is called Bacillus Anthracis. This formidable organism was shown to me by M. Pasteur in Paris last July. His recent investigations regarding the part it plays pathologically certainly rank amongst the most remarkable labours of that remarkable man. Observer after observer had strayed and fallen in this land of pitfalls, a multitude of opposing conclusions and mutually destructive theories being the result. In association with a younger physiological colleague, M. Joubert, Pasteur struck in amidst the chaos, and soon reduced it to harmony. They proved, among other things, that in cases where previous observers in France had supposed themselves to be dealing solely with splenic fever, another equally virulent factor was simultaneously active. Splenic fever was often overmastered by septicaemia, and results due solely to the latter had been frequently made the ground of pathological inferences regardi
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