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eme antivivisection party concerning all phases of biological experimentation. The weakest point in the antivivisection position has always seemed to me the condemnation of every kind of experimentation on animals, however painless. Yet how is it possible to expect public agreement with this position in every case? A few weeks ago, it was announced in the public press, that in one of the departments of Columbia University in New York, a series of experiments were being made to determine, if possible, the comparative food value of two articles in general use. If, for instance, a certain number of mice were fed from day to day upon pure butter, and an equal number upon the artificial product known as "oleo-margarine," would there be any perceptible difference in growth and general condition, and, if so, in favour of which group? This is an experiment upon animals; but it is one against which it would be difficult to bring forward any objection which the general public would very eagerly endorse. Distinctions must be made, between that which is cruel and that which is humane. "AGAINST PERFECTLY PAINLESS EXPERIMENT," said Sir Benjamin Ward Richardson, "carried out for purely experimental and great objects by men who themselves regret the necessity or expediency, and who only act under a strict sense of duty, no reasonable mind can raise an objection." On the other hand, let me reiterate acknowledgment of the vast indebtedness which the cause of humaneness owes to the opponents of all vivisection. Always and everywhere, the extremist helps in the progress of reform. But for a few hated and despised abolitionists, negro slavery might still be a recognized American institution; it was not Henry Clay or Daniel Webster who did most to hasten its downfall. That antivivisectionists have made mistakes, perhaps their most ardent advocate would be willing to concede. On the other hand, how great has been their service! But for extremists such as Frances Power Cobb of England and Elizabeth Stuart Phelps-Ward of America and a host of others whose hearts were aflame with indignation at cruelty and at the seeming duplicity which denied its existence, the whole question would have sunk into the abeyance in which in France or Germany, it to-day exists. They kept it alive. And what have not the antivivisectionists suffered by detraction, by ridicule, by misrepresentation and personal abuse! The most eloquent woman to whom I have e
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