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t. Although the evidence that milk may not infrequently serve as an agent in spreading disease is conclusive enough to satisfactorily prove the proposition, yet it should be borne in mind that the organism of any specific disease in question has rarely ever been found. The reasons for this are quite the same as those that govern the situation in the case of polluted waters, except that the difficulties of the problem are much greater in the case of milk than with water. The inability to readily separate the typhoid germ, for instance, from the colon bacillus, an organism frequently found in milk, presents technical difficulties not easily overcome. The most potent reason of failure to find disease bacteria is the fact that infection in any case must occur sometime previous to the appearance of the outbreak. Not only is there the usual period of incubation, but it rarely happens that an outbreak is investigated until a number of cases have occurred. In this interim the original cause of infection may have ceased to be operative. ~Typhoid fever.~ With reference to the diseases likely to to be disseminated through the medium of milk, infected after being drawn from the animal, typhoid fever is the most important. The reason for this is due (1) to the wide spread distribution of the disease; (2) to the fact that the typhoid bacillus is one that is capable of withstanding considerable amounts of acid, and consequently finds even in raw milk containing the normal lactic acid bacteria conditions favorable for its growth.[113] Ability to grow under these conditions can be shown not only experimentally, but there is abundant clinical evidence that even a slight infection often causes extensive outbreaks, as in the Stamford, Conn., outbreak in 1895 where 386 cases developed in a few weeks, 97 per cent. of which occurred on the route of one milk-man. In this case the milk cans were thoroughly and properly cleaned, but were rinsed out with _cold_ water from a shallow well that was found to be polluted. The most common mode of pollution of milk with typhoid organisms is where the milk utensils are infected in one way or another.[114] Second in importance is the carrying of infection by persons serving in the dual capacity of nurse and dairy attendant. ~Cholera.~ This germ does not find milk so favorable a nutrient medium as the typhoid organism, because it is much more sensitive toward the action of acids. Kitasato[115] found
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