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uberty and during adolescence, while in women it may take the place of menstruation and is sometimes more apt to occur at the menstrual periods; disorders of the nose have also been found to be aggravated at these periods. It has even been possible to control bleeding of the nose, both in men and women, by applying ice to the sexual regions. In both men and women, again, cases have been recorded in which sexual excitement, whether of coitus or masturbation, has been followed by bleeding of the nose. In numerous cases it is followed by slight congestive conditions of the nasal passages and especially by sneezing. Various authors have referred to this phenomenon; I am acquainted with a lady in whom it is fairly constant.[41] Fere records the case of a lady, a nervous subject, who began to experience intense spontaneous sexual excitement shortly after marriage, accompanied by much secretion from the nose.[42] J.N. Mackenzie is acquainted with a number of such cases, and he considers that the popular expression "bride's cold" indicates that this effect of strong sexual excitement is widely recognized. The late Professor Hack, of Freiburg, in 1884, called general medical attention to the intimate connection between the nose and states of nervous hyperexcitability in various parts of the body, although such a connection had been recognized for many centuries in medical literature. While Hack and his disciples thus gave prominence to this association, they undoubtedly greatly exaggerated its importance and significance. (Sir Felix Semon, _British Medical Journal_, November 9, 1901.) Even many workers who have more recently further added to our knowledge have also, as sometimes happens with enthusiasts, unduly strained their own data. Starting from the fact that in women during menstruation examination of the nose reveals a degree of congestion not found during the rest of the month, Fliess (_Die Beziehungen zwischen Nase und Weiblichen Geschlechtsorganen_, 1897), with the help of a number of elaborate and prolonged observations, has reached conclusions which, while they seem to be hazardous at some points, have certainly contributed to build up our knowledge of this obscure subject. Schiff (_Wiener klinische Wochenschrift_, 1900, p. 58, summarized in _British Medical Journal_, February 16, 1901), starting from a skeptical standpoint, has confirmed
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