porcelain filters, shows the presence of a poison which is capable of
producing the same results upon inoculation as the pure culture of the
bacillus itself. Zarniko, working upon the same organism, obtained a
number of positive results that led him to declare this bacillus is
the cause of epidemic diphtheria, in spite of many assertions to the
contrary. Chantmesse and Widal record the results of their work as to
what will most easily and effectively destroy the bacillus of
diphtheria.
The only three substances that actually checked and destroyed its
vitality were phenic acid (5 per cent.), camphor (20 per cent.), olive
oil (25 per cent.), in combination. For the last I substitute
glycerine, because this allows the mixture to penetrate farther into
the mucous membrane than oil, the latter favoring a tendency to pass
over the surface. This mixture when heated separates into two layers,
the upper one viscid and forming a sort of "glycerol," the lower
clear. The latter will completely sterilize a thread dipped in a pure
culture of the diphtheria bacillus. Corrosive sublimate was not
examined because in strong enough doses it would be dangerous and in
weaker ones it would be useless.
The facts obtained in regards to the streptococcus of erysipelas are
reported as follows: That both chemical and experimental evidence
teach the extreme ease of a renewed attack of the disease; that it is
possible to kill guinea pigs by an intoxication when they are immune
to an inoculation of the culture in ordinary quantities. And this
latter fact should warn experimenters trying to obtain immunity in man
by the inoculation of non-pathogenic bacteria, because the same
results may be reached.
A new theory in regard to fevers and the relation of micro-organisms
is suggested by Roussy, viz.: That it is a fermentation produced by a
diastase or soluble ferment found in all micro-organisms and cells,
and which they use in attacking and transforming matter, either inside
their substance or without it.
The resemblance of the malaria parasite to that of recurrent fever is
noted in the work of Sacharoff. He states that there exists in the
blood of those suffering from recurrent fever a haematozoon, which is
most prominent after the fever has begun to fall, when it is of
enormous proportions, twenty or more diameters of a red blood
corpuscle, although smaller ones may still be found. The parasite
consists of a delicate amoeboid body containin
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