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lueless by the holes made by the larvae. When fully mature they drop to the ground and complete their transformations. The sheep bot-flies (Fig. 32) lay their eggs in the nostrils of sheep. The larvae pass up into the frontal sinuses where they feed on the mucus, causing great suffering and loss. Many other species of animals are infested with their own particular species of bots. Several instances are recorded where the oxwarble has occurred in man, always causing much suffering and sometimes death. One or more species of bot-flies occurring in the tropical parts of America frequently attack man. The early larval stage soon after it has entered the skin is known as the _Ver macaque_. Later stages as _torcel_ or _Berne_. The presence of the larvae produces very painful and troublesome sores. It is supposed that the adult flies (one species of which is _Dermatobia cyaniventris_) lay their eggs on the skin which the larvae penetrate as soon as they hatch. It has also been suggested that they might reach the subcutaneous tissue by migrating from the alimentary canal as do some of the other bot-flies. A very serious eye disease, _Egyptian opthalmia_, is known to be spread by the house-flies and others. These flies are often abundant about the eyes, especially of children suffering from this disease. It is suspected that certain small flies (Oscinidae) in the southern part of the United States are responsible for the spread of disease known as "sore eye." FLEAS The fleas used to be considered as degenerate Diptera and were placed with that group but they are now classed as a separate order (Siphonaptera). Within recent years these little pests have come into special prominence on account of their importance in connection with the spread of the plague. The fact that they are so abundant everywhere and that they will so readily pass from one host to another makes the possibility of their spreading infectious diseases very great. Besides the kinds that are concerned in the transmission of plague, which are discussed in another chapter, there are many other kinds infesting various wild and domesticated animals and a few attacking birds. One of the most important of these is the jigger-flea or chigoe (_Dermatophilus penetrans_, Fig. 33). Various other names such as chigger-flea, sand-flea, jigger, chigger are also applied to this insect as well as to a minute red mite that burrows into the skin in much the same way as
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