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osis into another kind of substance. To prove that the number of these changes is bounded by no narrow limits, I need but refer to the rules of Permutation, which demonstrate that twelve letters of the alphabet may be arranged in no fewer than 479,000,000 different ways.[1] The elements are the letters of Nature's alphabet, their compounds are the words of the language of Creation. The combinations of sounds and of signs which express the ideas and sensations of man may be limited to millions; but numberless are the hieroglyphs by which the Divine wisdom and beneficence is inscribed on the pages of the magnificent volume of Nature. Of the sixty-six elementary bodies, not more than a dozen occur commonly in animal and vegetable substances; these are Oxygen, Hydrogen, Nitrogen, Carbon, Sulphur, Phosphorus, Chlorine, Silicium, Potassium, Sodium, Calcium, Magnesium, and Iron. In addition to these, Iodine, and sometimes Bromine, are found in plants which grow in or near the sea; and the former element has also been detected in some of the lower animals, and in land plants. Manganese, Lithium, Caesium, Rubidium, and a few others of the simple bodies, occasionally occur in plants and animals, but I believe their presence therein is always accidental. _Proximate Composition of Animal Substances._--The differences between vegetable and animal substances are often more apparent than real. Indeed many of the more important of these substances are almost identical in composition. The albumen which coagulates when the juices of vegetables are boiled, is identical with the albumen of the white of eggs; the fibrine of wheat is in no respect chemically different from the fibrine, or clot, of the blood; and, lastly, the legumine, or _vegetable caseine_, of peas is almost indistinguishable from the curd of milk, or _animal caseine_. But not only has chemical research demonstrated the identity of the albumen, fibrine, and caseine of vegetables with three of the more important constituents of animals, it has gone a step further, and proved that they differ from each other in but a few unimportant respects. They are unquestionably convertible into each other[2] within the animal organism; and their functions, as elements of nutrition, are almost, if not quite, identical. Exclusive of the blood, which contains the elements of every part of the body, the animal organism is composed of three distinct classes of substances--namely, _nitrog
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