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layer of the periosteum on the anterior aspect of the vertebrae, and extends along the surface of the bones, causing widespread superficial caries. It may attack the discs at their margins, and spread inwards between the discs and the contiguous vertebrae. Owing to the comparatively wide area of the spine implicated, this form of the disease is not attended with angular deformity, but rather with a wide backward curvature which corresponds in extent to the number of vertebrae affected. The accumulation of tuberculous pus under the periosteum and anterior longitudinal ligament is the first stage in the formation of the large abscesses with which this form of spinal tuberculosis is so commonly associated. _Effects on the Spinal Cord and Nerve Roots._--In some cases the cord and nerve roots are pressed upon by an oedematous swelling of the membranes; in others, the tuberculous process attacks the dura mater and gives rise to the formation of granulation tissue on its outer aspect--_tuberculous pachymeningitis_. Less frequently a collection of pus forms between the bone and the dura, and presses the cord back against the laminae. The cord is rarely subjected to pressure as a result of curving of the spine alone, but occasionally, especially in the cervical region, a sequestrum becomes displaced backward and exerts pressure on it, and it sometimes happens, also in the cervical region, that the cord is nipped by sudden displacement of diseased vertebrae--a condition comparable to a fracture-dislocation of the spine. The severity of the symptoms is aggravated by the occurrence of inflammation of the cord--_myelitis_--which is not due to tuberculous disease, but to interference with its blood-supply from the associated meningitis. _Repair._--When the progress of the disease is arrested, the natural cure of the condition is brought about by the bodies of the affected vertebrae becoming fused by osseous ankylosis (Fig. 211). While this reparative process is progressing, the cicatricial contraction renders the angular deformity more acute, and it may go on increasing until the bones are completely ankylosed; this reparative process can be followed in successive skiagrams. An increase in the projection in the back, therefore, is not necessarily an unfavourable symptom, although, of course, it is undesirable. [Illustration: FIG. 211.--Osseous Ankylosis of Bodies (_a_) of Dorsal Vertebrae, (_b_) of Lumbar Vertebrae followin
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