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ion of brain substance through an acquired opening in the skull and dura mater, such as may result from a compound fracture or a gun-shot wound. The protrusion is due to increased intra-cranial tension, and is almost invariably associated with infection of the brain and its membranes, and with the presence of a foreign body or fragments of bone. Other things being equal, a hernia is more likely to occur through a small than through a large opening in the skull. So long as the extruded portion of brain matter is small, it pulsates, but as it increases in size and is pressed upon by the edges of the opening through which it escapes, the pulsation ceases, and the herniated portion may become strangulated and undergo necrosis. In cases of compound fracture, and in other conditions associated with necrosis of bone, masses of redundant granulation tissue growing from the soft parts outside the skull may simulate a hernia cerebri. The _treatment_ consists in counteracting the septic infection by purifying the protruding mass, and if necessary by enlarging the opening in the skull with rongeur forceps to admit of the removal of foreign bodies or bone fragments and to relieve the inter-cranial tension. Steps must also be taken to prevent meningitis, which, if it occurs, is usually fatal. Pressure over the hernia, with the object of returning it to the skull, is to be avoided, and the herniated portion should not be cut away unless it is sloughing, or has become pedunculated. It may be got rid of by painting it with 40 per cent. formalin, which causes a dry, horny crust to form on the surface; this is picked off, and the formalin re-applied. After the hernia has disappeared and the wound is aseptic, steps should be taken to close the gap in the skull. This may be done by an osteo-plastic operation in which a flap, comprising a segment of the outer table, is raised from an adjacent part of the skull and placed in the gap; or by transplanting a portion of periosteum-covered bone from the scapula, tibia, or other suitable source. An alternative method is to implant a plate of celluloid, silver or other metal, or a portion of the fascia lata, in the gap. When a permanent hole is left in the bone, the patient should wear over it a leather or metal shield to protect the brain. The protrusion of brain resulting after a decompression operation deliberately performed for the relief of intra-cranial tension, unless it becomes in
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