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the walls of a crowded room is potentially a productive focus for microbes. Every deposit of dirt on persons, clothing, or furniture is also a productive focus, and production is fostered in close apartments by the warmth and moisture of the place. In hospitals productive foci are more numerous than in ordinary dwellings. If microbes are present in the breath of ordinary individuals, what can we expect in the breath of those whose lungs are rotten with tubercular disease? Then we have the collections of expectorated matter and of other organic secretions, which all serve as productive foci. Every wound and sore, when antiseptic precautions are not used, becomes a most active and dangerous focus, and every patient suffering from an infective disease is probably a focus for the production of infective particles. When we consider, also, that hospital wards are occupied day and night, and continuously for weeks, it is not to be wondered at that microbes are abundant therein. I want especially to dwell upon the fact that foci, and probably productive foci, may exist outside the body. It is highly probable, judging from the results of experiments, that every collection of putrescible matter is potentially a productive focus of microbes. The thought, of a pit or sewer filled with excremental matters mixed with water, seething and bubbling in its dark warm atmosphere, and communicating directly (with or without the intervention of that treacherous machine called a trap) with a house, is enough to make one shudder, and the long bills of mortality already chargeable to this arrangement tell us that if we shudder we do not do so without cause. As an instance of the way in which dangers may work in unsuspected ways, I may mention the fact that Emmerich, in examining the soil beneath a ward of a hospital at Amberg, discovered therein the peculiar bacillus which causes pneumonia, and which had probably been the cause of an outbreak of pneumonia that had occurred in that very ward. The importance of "Dutch cleanliness" in our houses, and the abolition of all collections of putrescible matter in and around our houses, is abundantly evident. It will not be without profit to examine some well-known facts, by the aids of the additional light which has been thrown upon them by the study of the microbes which are in the media around us. There is no better known cause of a high death rate than overcrowding. Overcrowding increases t
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