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ation to the surroundings in which they find themselves, namely, the tissues and body-fluids of some particular host whom they attack, bring certain limitations with them. Just in so far as they have adjusted themselves to live in and overcome the opposition of the body-tissues of a certain species of animals, _just to that degree they have incapacitated themselves to live in the tissues of any other species_. Some of the most interesting and far-reachingly important work that has been done in the bacteriology of tuberculosis of late years has concerned itself with the changes that have taken place in different varieties and strains of tubercle bacilli as the result of adjusting themselves to particular environments. The subject is so enormous that only the crudest outlines can be given here, and so new that it is impossible to announce any positive conclusions. But these appear to be the dominant tendencies of thought in the field so far. Though nearly all domestic animals and birds, and a majority of wild animals under captivity, are subject to the attack of tuberculosis, practically all the infections hitherto studied are caused by one of three great varieties or species of the tubercle bacillus: the _human_, infesting our own species; the _bovine_, attacking cattle; and the _avian_, inhabiting the tissues of birds, especially the domestic fowl. These three varieties or species so closely resemble one another that they were at one time regarded as identical, and we can well remember the wave of dismay which swept over the medical world when Robert Koch announced that the "_perlsucht_" of cattle was a genuine and unquestioned tuberculosis due to an unmistakable tubercle bacillus. But as these varieties were thoroughly and carefully studied, it was soon found that they presented definite marks of differentiation, until now they are universally admitted to be distinct varieties, each with its own life peculiarities, and, according to some authorities, even distinct species. "But," we fancy we hear some one inquire impatiently, "what do those academic, technical distinctions matter to us? Whether the avian tuberculosis germ is a variety or a true species may be left to the taxonomists, but it is of no earthly importance to us." On the contrary, it is of the greatest importance. For the distinctive feature about a particular species of parasite is that it will live and flourish where another species will die, and,
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