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er against them, for in no known civil epidemic has the number of those who caught the disease exceeded ten per cent of the total number drinking the infected water or milk. In one or two camps in time of war the percentage has risen as high as eighteen or twenty per cent of those exposed, but this is exceptional. However, now that we know that intestinal symptoms do not constitute the entire disease, and may even be entirely absent, we strongly suspect that many cases of slight depression, with feverishness, loss of appetite, and disturbances of the digestion, which occur during an epidemic, may really have been very mild cases of the disease. One of the singular features of the disease is that, unlike many other infections, we are entirely unable to say what conditions or influences seem either to protect against it or to predispose toward it. In the days when we believed it to be an exclusively intestinal disease it was naturally supposed that chronic digestive disturbances, and especially acute attacks of bowel trouble or dysentery, would predispose to it, but this has been entirely disproved. Soldiers in barracks with chronic digestive disturbances, and even with dysentery, have shown no higher percentage of typhoid during an epidemic than others. Nor does it seem much more likely to occur in those who are constitutionally weak, or run down, or overworked, as some of the most violent and unmanageable cases occur in vigorous men and women, who were previously in perfect health. So that, although we have unquestionably a high degree of resistance against it, since not more than one in ten exposed contracts it, and only one in ten of those who contract it dies, we have not the least idea in what direction, so to speak, to build up our resisting powers in order to increase them. The best remedy is to destroy the disease altogether, and this could be done in five years by intelligent concerted effort. It was at one time supposed that typhoid fever was a disease exclusively confined to adult life; but it is now known to occur frequently in children, though often in such a mild and irregular form as to escape recognition. Something like seventy per cent of all cases occur between the fifteenth and the fortieth year, and it is, for some reason, though rarer, peculiarly serious and more often fatal after the fiftieth year. When once the outer wall has been pierced, the sack of the city rapidly proceeds. The bacilli mu
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