. The oblique openings--passages for the venae vorticosae--are
said to be narrowed. The openings for the passage of the anterior
ciliary vessels are enlarged in many, particularly in advanced cases.
Minute herniae at these openings are sometimes present. Dilatation and
tortuosity of the anterior ciliary veins are due apparently to excessive
flow of blood through them on account of the abnormally small amount
carried off by the venae vorticosae. In the stage of degeneration,
ectasae of the sclera occur most frequently near the equator of the
globe. Spontaneous rupture may take place.
_Anterior Chamber._ The anterior chamber is shallow, as a rule. This is
almost without exception in primary glaucoma in adults. In secondary
glaucoma in which occlusion of Fontana's spaces occurs as a result of
the deposition of fibrin or other inflammatory products the anterior
chamber may be of normal depth, or deeper than normal. Very deep
anterior chamber may occur in glaucoma, due to retraction of lens and
iris following fibrinous or plastic exudation into the vitreous, or
when it occurs in congenital glaucoma, due to enlargement of the globe.
_Aqueous Humor._ The aqueous humor, as has been pointed out by
Uribe-Troncoso (Pathoginie du Glaucome 1903) contains a greatly
increased quantity of albuminoids and inorganic salts in glaucoma. In
acute glaucoma the increase of albuminoids (blood proteids) is greater
than in chronic glaucoma. The aqueous humor becomes slightly turbid in
acute attacks, coagulating more readily than the normal. The plastic
principle contained in the aqueous is rarely sufficient to cause
adhesion between the margin of the iris and the lens capsule, but the
colloid nature of the aqueous, according to Troncoso, lessens its
diffusibility and prevents its free passage into the lymph channels. The
increase in albuminoids is a consequence of congestion and venous stasis
and does not precede the attack.
_Filtration Angle._ The changes that occur in the filtration angle
before it is encroached upon by iris tissue are sclerosis of the
ligamentum pectinatum in adults to which Henderson (Trans. Ophth. Soc.
U.K. Vol. xxviii) has called our attention; the accompanying sclerosis
of the other tissues to the inner side of Schlemm's canal; and, in some
cases, the deposition of pigmented cells derived from the iris and
ciliary processes (Levinsohn) which serve to obstruct the lymph spaces.
In many of the cases of acute glaucoma a
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