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lood pressure below his pathological norm than there is for reducing it below his physiological norm. The adjustment of a man's blood pressure to his pathological norm often has to be as correctly done as the adjustment of a watch which is losing or gaining time." I shall not quote Hare's elaborate methods for determining these various points because they do not belong to a paper of this character, but I quote his admirable advice because it emphasizes what I believe to be an essential in the treatment of chronic glaucoma, exclusive of operative work, that is, the intelligent co-operation of the oculist and the internist. Some such thought was in the mind of Ibershoff, who quotes Sterling and Henderson's views that the rate of secretion depends upon and varies with the difference in the blood pressure and the tension of the eyeball, and that the specific gravity of the secretion increases directly with the blood pressure and inversely with the ocular tension. Should the blood pressure be very high, paracentesis, for example, would apparently not be the proper procedure, and the resulting difference produced between the blood pressure and the eye tension would cause a rapid reformation of fluid with higher specific gravity and higher osmotic coefficient. The proper procedure in these circumstances is first properly to reduce the blood pressure, or what I have, quoting Hare, ventured to call the over plus pressure. 4. _The relation of osmosis, lymphagogue activity, absorption of edema, capillary contractility and decreased affinity of ocular colloids for water to the reduction of increased intra-ocular tension._ We are all familiar with the attention which was directed some years ago to the statements coming from French clinics that the treatment of glaucoma should include the administration of osmotic substances as adjuvants in the reduction of increased intra-ocular tension. Particularly was this treatment advocated by Cantonnet in the administration of daily doses of 3 grams of chlorid of sodium, preceded, of course, by a careful urinary examination and the estimation of the amount of urine and its contained chlorids. Carefully this dose was increased in proper circumstances to 15 grams per diem, and in Cantonnet's original paper good results were achieved in 12 of the 17 patients so treated. I have myself experimented somewhat, not with the administration of sodium chlorid by the mouth, but with the introduction
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