g periods of
several years, so as to appreciate the amount of immunity that should
follow.

Between the 30th of June, 1881, and the 2d of December, 1893,
eighty-eight persons have been so inoculated. All were white adults,
uniting the conditions which justify the assumption that they were
susceptible to yellow fever. Only three were women. The chronological
distribution of the inoculations was as follows: seven in 1881, ten in
1883, nine in 1885, three in 1886, twelve in 1887, nine in 1888, seven
in 1889, ten in 1890, eight in 1891, three in 1892, and ten in 1893.

The yellow fever patients upon whom the mosquitoes were contaminated
were, almost in every instance, well-marked cases of the albuminuric or
melanoalbuminuric forms, in the second, third, fourth, fifth, or sixth
day of the disease. In some of the susceptible subjects, the inoculation
was repeated when the source of the contamination appeared uncertain.

Among the eighty-seven who have been under observation, the following
results have been recorded:

Within a term of days, varying between five and twenty-five after the
inoculation, _one_ presented a mild albuminuric attack, and _thirteen,
only_ "acclimation fevers."

* * * * *

While Finlay's theory appeared to be plausible and to explain many of
the facts relating to the etiology of yellow fever, his experimental
inoculations not only failed to give it substantial support, but the
negative results, as reported, by himself, seemed to be opposed to the
view that yellow fever is transmitted by the mosquito. It is true that
he reports one case which "presented a mild albuminuric attack" which we
may accept as an attack of yellow fever. But in view of the fact that
this case occurred in the city of Havana, where yellow fever is endemic,
and of the eighty-six negative results from similar inoculations, the
inference seemed justified that in this case the disease was contracted
in some other way than as a result of the so-called "mosquito
inoculation." The thirteen cases in which only "acclimation fevers"
occurred "within a term of days varying between five and twenty-five
after the inoculation" appeared to me to have no value as giving support
to Finlay's theory; first, because these "acclimation fevers" could not
be identified as mild cases of yellow fever; second, because the
ordinary method of incubation in yellow fever, is less than five days;
and, third, because these ind