FREE BOOKS

Author's List




PREV.   NEXT  
|<   50   51   52   53   54   55   56   57   58   59   60   61   62   63   64   65   66   67   68   69   70   71   72   73   74  
75   76   77   78   79   80   81   82   83   84   85   86   87   88   89   90   91   92   93   94   95   96   97   98   99   >>   >|  
fford another means of conversion of one sugar into another. From the standpoint of physiological processes, _glucuronic acid_ is the most interesting and important oxidation product of glucose. It is often found in the urine of animals, as the result of the partial oxidation of glucose in the animal tissues. Normally, glucose is oxidized in the body to its final oxidation products, carbon dioxide and water. But when many difficultly oxidizable substances, such as chloral, camphor, turpentine oil, aniline, etc., are introduced into the body, the organism has the power of combining these with glucose to form glucosides. These so-called "paired" compounds are then oxidized to the corresponding glucuronic acid derivatives and eliminated from the body in the urine. No phenomenon similar to this occurs in plants, however, and glucuronic acid has never been found in plant tissues. =Synthesis and Degradation of Hexoses.=--Monosaccharides of any desired number of carbon atoms can be produced from aldoses having one less carbon atoms, by way of the familiar "nitrile" reaction. Aldoses, like all other aldehydes, combine directly with hydrocyanic acid, forming compounds known as nitriles, which contain one more carbon atom than was present in the original aldehyde; the cyanogen group can easily be converted into a COOH group; and this, in turn, reduced to an aldehyde, thus producing an aldose with one more carbon atom than was present in the initial sugar. These changes may be illustrated by the following equations: (1) CHO + HCN CHOH.CN CN | | | (CHOH)_{3} = (CHOH)_{3} or (CHOH)_{4} | | | CH{2}OH CH_{2}OH CH_{2}OH Aldopentose Nitrile (2) CN + H_{2}O COOH + NH_{3} | | (CHOH)_{4} = (CHOH)_{4} | | CH_{2}OH CH_{2}OH Nitrile Acid (3) COOH - O CHO | | (CHOH)_{4} = (CHOH)_{4} | | CH_{2}OH CH_{2}OH Acid Aldohexose It is possible, by this process, to advance step by step from formaldehyde
PREV.   NEXT  
|<   50   51   52   53   54   55   56   57   58   59   60   61   62   63   64   65   66   67   68   69   70   71   72   73   74  
75   76   77   78   79   80   81   82   83   84   85   86   87   88   89   90   91   92   93   94   95   96   97   98   99   >>   >|  



Top keywords:

carbon

 

glucose

 

oxidation

 

glucuronic

 
aldehyde
 

Nitrile

 

present

 
oxidized
 

tissues

 
compounds

reaction

 

Aldoses

 
nitrile
 

familiar

 

forming

 
hydrocyanic
 

directly

 
aldehydes
 

combine

 

nitriles


Aldopentose

 

equations

 

advance

 
formaldehyde
 

process

 

Aldohexose

 

illustrated

 

converted

 

easily

 

cyanogen


reduced

 

initial

 

aldose

 

producing

 

original

 

plants

 
dioxide
 
products
 
difficultly
 

camphor


turpentine
 

chloral

 

oxidizable

 

substances

 

Normally

 

animal

 

standpoint

 

physiological

 

processes

 

conversion