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ich by most readers will be considered of superlative authority as to one important part of the case: In Stowe's Survey of London, vol. ii. p. 7, is preserved a copy of the rules or regulations established by parliament in the eighth year of Henry the Second, for the government of the licensed stews in Southwark, among which I find the following: "No stewholder to keep any woman that hath the perilous infirmity of burning." This was 330 years before the voyage of Columbus. If this "perilous infirmity of burning" be the disease now denominated the Lues Venerea, the question is solved as to the concern of America in its production. And all that Oviedo, Guicciardin, Charlevoix, and others say, as to its first appearance in Europe, when the king of Spain sent an army to the assistance of Ferdinand the Second of Naples, must be reckoned as applicable only to its greater frequency, or more common occurrence, than had before been known. But, indeed, the description given of the disease which then prevailed so alarmingly, is with some difficulty reconcileable to what is now ascertained of the venereal infection. Guicciardin himself seems to hint at a diversity in its form and mode of reception, betwixt the period he assigns for its appearance, and "after the course of many years." "For then," says he, (the quotation is made from Fenton's curious translation, London, 1599) "the disease began to be less malitious, changing itself into diverse kindes of infirmity, _differing from the first calamity_, whereof truly the regions and people of our times might justly complain, _if it happened to them without their proper disorder_ (that is, without their own fault,) seeing it is well approved by all those that have diligently studied and observed the properties of that evil, that either never or very rarely it happeneth to any otherwayes, than by contagious whoredome or immoderate incontinency." That a mistake exists in the early accounts as to the nature of the disease which was found at Hispaniola by the Spaniards, and by them on their return to Europe communicated to the French and Neapolitans, is very probable from the circumstance mentioned in them, that some vegetable substances, especially _guiaicum_, were effectual for its cure;--since it is most certain, that the Lues Venerea of modern times is not at all destructible by such means, whereas there are several cutaneous affections which may be benefited by them. A similar remark m
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