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heart, blood vessels, and kidneys. Degeneration of tissues is normally a condition typical of old age, and in aged persons it may occur in any tissue. There is no elixir of youth, and for old age there is no cure. But the important facts in this connection are that degenerative changes now occur prematurely, and that among a vast number of people, in various classes of society and various occupations, the vital organs show a marked tendency to break down after the age of 45. This condition is not inevitable. Before the beginning of the present war, death rates at all ages were decreasing in England, Sweden, and other European countries. In America also degenerative diseases can be checked or prevented to a large extent, and it is highly important that their causes should be generally understood. The two groups following include some of the probable causes: 1. Conditions of life which result in continued overwork, and mental overwork in particular; worry, excitement, insufficient recreation and exercise, and other kinds of nervous strain typical of modern life, especially in cities. 2. Irritating substances in the body, including poisonous substances resulting from infectious diseases, and from syphilis in particular; poisons from chronic infections, alcohol, and industrial poisons such as lead and other metals; overeating and improper eating, especially of meat and other proteins, and rich or highly seasoned food; faulty digestion, constipation, and imperfect elimination through the kidneys.--(See Dr. A. E. Shipley, in bulletin of the N. Y. City Dept. of Health, Feb., 1915.) The importance of early recognition cannot be overemphasized. In many of these troubles the symptoms are not pronounced, and the victims have no knowledge of their condition until they happen to be examined for life insurance, or until the disease is far advanced. And even when they realize that trouble exists, as for example constipation or overwork, most people absolutely fail to realize how serious the consequences may be. The first step toward remedy is periodic complete physical examination by a competent physician, in order to learn in time how to prevent these degenerative diseases, if present, from growing worse. The custom of undergoing an annual physical examination is becoming more common, and "such a course, conservatively estimated, would add 5 years to the average life of persons between 45 and 50."--(Winslow.) "Rece
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