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, produce acids and other materials injurious to themselves. Furthermore, lack of proper food, moisture, or favorable temperature, and competition with other organisms tend to prevent their unrestricted growth and multiplication. [Illustration: FIG. 5.--BACTERIA WITH SPORES. (_Williams._)] SPORES.--Most bacteria die if conditions become unfavorable to their growth, but some enter into a resting stage. This stage is characterized by the development of round or oval glistening bodies called spores, which are of dense structure and possess an extraordinary power to withstand heat, chemicals, and unfavorable surroundings. Except in rare instances a single cell produces but one spore. As soon as favorable conditions of temperature, moisture, and food supply are restored, the spore develops into the active form of the germ; it may, however, remain dormant for months or years. Spore formation, however, occurs in only a very few varieties of pathogenic bacteria. DISTRIBUTION.--Bacteria are very widely distributed in nature; they are in fact found practically everywhere on the surface of the earth. They are present in plants and water and food; on fabrics and furniture, walls and floors; and they are found in great numbers on the skin, hair, many mucous surfaces, and other tissues of the body. PROTOZOA The protozoa are the lowest group of the animal kingdom. Like bacteria they are composed of single cells so small as to be visible only under the microscope. They play an important part in causing certain diseases of man, especially in the tropics. Among the well-known human diseases of protozoan origin are malaria, amoebic dysentery, and sleeping-sickness. Protozoa also cause several wide-spread and serious plagues of domestic animals. VISIBLE PARASITES A few diseases are caused by parasites large enough to be seen with the naked eye. One of the most important is hookworm disease. This disease is caused by a tiny worm which penetrates the victim's skin and ultimately finds its way into the intestine. Other diseases also are caused by parasitic worms, such as tapeworms, pinworms, and trichinae. The latter are acquired as a result of eating infected meat, particularly infected pork that has not been thoroughly cooked. TRANSMISSION OF PATHOGENIC ORGANISMS Pathogenic or disease producing organisms need for their development food, moisture, darkness, and warmth, conditions that exist within the human body. Wh
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