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of it during the year 1897. Death rates from diphtheria and typhoid fever have been greatly reduced by the use of antitoxin and antityphoid vaccine. Thus in New York State in 1894, before antitoxin was generally used, 99 out of every 100,000 of the population died of diphtheria, while only 20 out of 100,000 died of it in 1914. In 1911 a United States Army Division of more than 12,000 men camped at San Antonio, Texas, for four months. All of these men were vaccinated against typhoid fever and only a single case occurred during the summer, although conditions of camp life always tend to spread the disease. While many and various factors tend to lower resistance rather than to increase it, the idea that these factors act equally in all kinds of infection is erroneous. "The principal causes which diminish resistance to infection are: wet and cold, fatigue, insufficient or unsuitable food, vitiated atmosphere, insufficient sleep and rest, worry, and excesses of all kinds. The mechanism by which these varying conditions lower our immunity must receive our attention, for they are of the greatest importance in preventive medicine. It is a matter of common observation that exposure to wet and cold or sudden changes of temperature, overwork, worry, stale air, poor food, etc., make us more liable to contract certain diseases. The tuberculosis propaganda that has been spread broadcast with such energy and good effect has taught the value of fresh air and sunshine, good food, and rest in increasing our resistance to this infection. "There is, however, a wrong impression abroad that because a lowering of the general vitality favors certain diseases, such as tuberculosis, common colds, pneumonia, septic and other infections, it plays a similar role in all communicable diseases. Many infections, such as smallpox, measles, yellow fever, tetanus, whooping-cough, typhoid fever, cholera, plague, scarlet fever, and other diseases, have no particular relation whatever to bodily vigor. These diseases often strike down the young and vigorous in the prime of life. The most robust will succumb quickly to tuberculosis if he receives a sufficient dose of the virulent micro-organisms. A good physical condition does not always temper the virulence of the disease; on the cont
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