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ulcer becomes of considerable size, and assumes a frightful aspect. The patient becomes dejected in his spirits, his countenance is sallow and woe worn, his appetite fails, his days and nights are full of sorrow and pain, the disease still progresses, till, finally, death comes to the aid of the unhappy sufferer, and closes the scene of anguish and misery. Such is the progress of this appalling malady. It commences apparently in a trifling way, it terminates in destruction of life. I have said that the patients' spirits are usually dejected in this disease, and I wish this to be particularly noticed, as it points out how cautious a medical man ought to be in stating positively to the sufferer the real nature of his complaint. The mind is so depressed by the disease, that the simple communication of the fact to the patient often produces such a shock to the feelings as he rarely recovers from; indeed, it often accelerates the death of the patient, and such being the case, I am quite certain that no man of experience, judgment, or common sense, would ever commit himself so seriously. Whenever it is done, it is usually committed by some daring unprincipled empiric, who often finds it to his interest to pronounce a case cancerous when in 99 cases out of 100 it is really not so. Now, with respect to the cure of cancer, I can confidently assert, that when the disease is really cancer, when it occurs as a constitutional disease, (as it almost always does) and when it is perfectly developed, no known remedy is in existence which has the power of destroying it. It sets even the knife at defiance, for I have repeatedly seen that when the disease has been scientifically extirpated, it either returns to the same part, or to the neighbourhood of the same part, and in such cases the disease has generally proceeded in its second attack with extraordinary rapidity. I am strengthened in this assertion by the observations of Professor Monro--he says, "_Of nearly sixty cancers which I have been present at the extirpation of, only four patients remained free of the disease for two years. Three of these lucky people had occult cancers in the breast, and the fourth had an ulcerated cancer of the lip. The disease does not always return to the part where the former tumour was taken away, but more frequently in the neighbourhood, and sometimes at a considerable distance. Upon a relapse, the disease in those I saw was more violent, and made
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