some had a slight Delirium in the Time of
the Paroxysms, and the Pulse was not quite settled in the Intervals.
In such Cases, where the Patient was strong, nothing answered so well
as to take away some Blood; and to give the saline Draughts with Nitre
till the Fever was moderated, before we gave the Bark.

In general, there is a Prejudice against bleeding in Agues, after they
become regular; but I have always observed, both in _England_ and in
_Germany_, that where Patients are strong and plethoric, and the
Fever in the Paroxysms rises high, or the Pulse remains quick in the
Intervals, that taking away more or less Blood, and giving the
antiphlogistic Medicines in the Beginning, eased the Patient,
moderated the Fever, and made it safer to give the Bark soon; and I
never saw the least Inconvenience from the Practice; but, on the
contrary, have seen several Intermittent Fevers change into continued
ones from the Neglect of this Evacuation; and have seen Cases where
the Bark, instead of stopping the Ague, rather increased the Fever,
till the Patient was blooded, and had pursued the antiphlogistic
Method for some Time; after which the Bark had its proper Effect, and
put an End to the Disorder.

As soon as these Agues became regular, and the Patient was quite cool,
and free from any Fever in the Intervals, we gave the Bark; which soon
put a Stop to the Paroxysms, without the least bad Consequences; but,
before giving the Bark, we always took Care to empty the first
Passages by the Use of Emetics and Purgatives, where there was no
Symptom to forbid their Use: In Cases where the Patient was weak, and
the Fits so violent as to make it necessary to stop the Ague, before
we had Time to administer Emetics or Purgatives, we added so much
Rhubarb to the first Doses of the Bark as procured the Patient some
loose Stools, as recommended by Dr. _Mead_[82]; which did not prevent
its stopping the Ague, at the same Time that it answered the End
proposed of carrying off any putrid Humours that might be lodged in
the Intestines.

[82] Mr. _Cleghorn_, while at _Minorca_, after Evacuations,
gave the Bark at the End of the third Period, as we observed
before; but where the Fever had been neglected till about the
third or fourth Period, or badly treated in the Beginning,
and the Bowels were inflamed or overcharged with corrupted
Gall, he was obliged to endeavour to palliate the most
pressing Complaints, and to wat