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out before, analogy has been confounded with identity. When a dog, for instance, has been bitten by a snake he does not usually collapse as quickly as a human being, but is able to drag himself about much longer before his hind legs refuse their service and he is unable to walk. This longer duration of the first stage of the poisoning process is no doubt owing to a higher organisation and greater functional power of the motor nerve centres of dogs. The amount of motor force at their disposal is greater, and hence they offer greater resistance to the invader seeking to turn off this force. When finally the latter gains the ascendency, irregular discharges of motor nerve force still take place and find their expression in convulsions, which in man only exceptionally occur. But the difference between man and dog becomes more marked yet when strychnine is administered to a dog suffering from snake-poison. It counteracts the latter quite as effectually in a dog as in man, but has to be injected with extreme caution, for whilst in man a slight excess in the quantity required to subdue the snake-virus is not only harmless, but actually necessary, any excess of it in a dog will at once produce violent tetanic convulsions and cause the animal to die even quicker than the snake-poison would have killed it, if allowed to run its course. In the face of these facts the judiciousness of the proposal lately made both here and in India to subject the strychnine treatment of snakebite once more to a series of test experiments on animals appears more than questionable. Another cause that has largely contributed to render experiments on animals so barren of results must be sought in the injudicious selection of substances intended to serve as antidotes. It is simply impossible to act on an organic compound like snake-poison, coursing through a living system, by chemicals that will either combine with it or decompose it in a manner likely to deprive it of its deadly qualities and render it innocuous. Yet what do we find? Acids and alkalis, arsenic, bromides and iodides, chlorine, mercurial preparations, &c., &c., have been poured into the luckless animals as if they were so many test tubes. A chemical antidote, a substance possessing special affinity to snake-poison and by means of this affinity combining with it in some mysterious and incomprehensible manner, one can hardy imagine to exist. Physiological antidotes, on the other hand, sub
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