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ion, assuming as a working hypothesis that there is but one law for all snake-poison and not several ones, just as there is one law for the structure of these reptiles, admitting of variations, but not of absolute divergence from the general plan. The shortest and surest way to find this law is close observation and careful analysis of the symptoms produced by the poison on man, and as the opportunities for such observation are not of frequent occurrence to the individual, co-operation and careful comparison of notes on the part of many observers. This method of investigation, which, during the last few years, has been pursued in Australia with most satisfactory results, was never practised anywhere else, not even in America, but instead of it each observer, with few exceptions, kept his own notes to himself, and if there happened to be one here and there hungry for more knowledge than his scanty opportunities for observation on man would supply, his resort was usually experiments on animals. A few snakes were caught, a few luckless dogs or other animals procured, and the slaughter of the innocents began. As test experiments to confirm observations on man, or made with a view of finding a correct theory of the action of snake-poison, these attempts were unobjectionable, although, without an elaborate scientific apparatus and in other than skilled hands, they were not likely to produce results of any value. But most of the experimenters were not content with purely theoretical aims. They were seeking to find the antidote by a purely empirical method, and had nothing to guide them in the choice of drugs. A dose of snake-poison was administered to an animal, and then a dose of some drug or chemical, chosen _ad libitum_, sent after it. Next day another presumed antidote was tried, another animal slaughtered, and so on _ad nauseam_, until finally the baffled antidote-searcher, not one whit the wiser for all his trouble and the useless tortures inflicted, confessed himself beaten and joined in the "_non possums_" of his predecessors. One important point has been completely left out of sight and ignored in all this experimenting on animals. It is the fact that the action of snake-poison on the human system and on that of animals, more especially dogs, though very similar, is not absolutely identical, and that for this reason alone results of experiments on the latter cannot be indiscriminately applied to man. As pointed
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