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rors during this period may only appear to exert a local influence, causing disturbance which may readily be relieved, but the danger is in laying too little stress upon these disturbances, forgetting that the delicate organism of a child may be permanently injured by a constant disregard of nature's mandates. In the words of the old adage, the pitcher may go once too often to the well, and an injured digestive apparatus is even more difficult to mend than the proverbial pitcher. In this section, then, the metabolic changes due to pathological conditions and the dietetic treatment thereof will be discussed. ~Age and Weight.~--As has already been stated, there are certain points to be kept in mind in attempting to provide an adequate diet for the human machine; _First_, the _age_ and _weight_. The gain during infancy should be steady--an allowance of 40 calories per pound of body weight to cover the energy requirements and 4 protein calories per pound to cover the nitrogen needs. During the second and third years the energy requirements will be covered by 30 to 40 calories per pound and the nitrogen needs by 3 to 4 protein calories per pound. From the fifth to the eighth year the nitrogen needs continue to be covered by 3 to 4 protein calories per pound and the energy requirements by 35 to 37 calories per pound during the fifth year; 32 to 34 calories per pound during the seventh year. After the body has reached its full development its requirements will be met if sufficient protein is provided to cover its maintenance needs and if the energy calories are regulated according to the amount of exercise taken, keeping in mind that the energy requirements of a man at rest (sitting) will be about 2,000 calories per day and that exercise, especially that taken in the open air, raises the energy needs of the body. ~Daily Gain.~--In estimating the relative daily gain in body weight of children of different ages, Mendel[64] gives the following table: TABLE In the first month, about 1.00 per cent At the middle of the first year 0.30 per cent At the end of the first year 0.15 per cent At fifth year 0.03 per cent Maximum in later years for boys 0.07 per cent Maximum in later years for girls 0.04 per cent ~Retention of Nitrogen in Infancy.~--When the baby is gaining in weight and strength there is a retention of both nitrogen and salts, and when the baby is not ga
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