at some great change was about to take place within him. At the
expiration of the third minute, he _lost sensibility and consciousness_.
In this state he remained two minutes. The pulse was unaffected. Upon
coming to himself, he felt a general sense of exhaustion, with weakness
of the back and knees. For the remainder of the day he walked
unsteadily, and his mind was confused.

A. T., aged thirty-six, a tall strong servant-maid, after inhaling for
seventeen minutes, became unconscious, and appeared not to feel a
trifling wound with a surgical needle. In a minute consciousness
returned. She laughed immoderately, spoke of an agreeable feeling of
warmth, and said she had had pleasant dreams. The pulse was slower, the
breathing deeper, during the inhalation. The same person upon inhaling,
on another occasion, with a better apparatus, became insensible after
two minutes. The eyes appeared red and suffused; a carious tooth was
then extracted, which caused her to moan slightly. On returning to
herself she complained of giddiness, but said she had experienced none
but agreeable feelings. She had no idea that the tooth had been
extracted.

K. A., aged twenty-nine, upon beginning the inhalation, showed signs of
excitement, but in nine minutes lay relaxed like a corpse. A tooth was
extracted. Two minutes afterwards she awoke, moaning and disturbed. She
stated that she _had not felt the extraction of the tooth, but she had
heard it_.

C. S., aged twenty-two, a strong and healthy young man, a student of
surgery, on commencing the inhalation, coughed, and there was a flow of
saliva and of tears. In three and a half minutes the skin appeared
insensible to pain. Consciousness remained perfect and undisturbed. The
skin was warm; the eyes were open; the hearing as usual; the speech,
however, was difficult. This state continued eighteen minutes, during
which, at _his request_, two teeth with large fangs were extracted. He
held himself perfectly still. He said, afterwards, that _he felt the
application of the instrument, but was sensible of no pain_, during the
extraction of the teeth.

W. S., aged nineteen, a strong and healthy young man, a law-student,
after inhaling the ether-vapour a minute, began to move his arms about,
struck his knees, stamped with his feet, laughed. In three minutes the
laughter and excitement had increased. The eyes rolled, he sprang up,
talked volubly; the pulse was strong and frequent. In seven minutes he
b