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with the Duke of Argyll (see Nature, January 16, 1890, et seq.) was that there was no evidence in support of the transmission of any acquired modification. The orthodoxy of science, therefore, must be held as giving at any rate a provisional support to Professor Weismann, but all of them, including even Professor Weismann himself, shrink from committing themselves to the opinion that the germ-cells of any organisms remain in all cases unaffected by the events that occur to the other cells of the same organism, and until they do this they have knocked the bottom out of their case. From among the passages in which Professor Weismann himself shows a desire to hedge I may take the following from page 170 of his book:-- "I am also far from asserting that the germ-plasm which, as I hold, is transmitted as the basis of heredity from one generation to another, is absolutely unchangeable or totally uninfluenced by forces residing in the organism within which it is transformed into germ-cells. I am also compelled to admit it as conceivable that organisms may exert a modifying influence upon their germ-cells, and even that such a process is to a certain extent inevitable. The nutrition and growth of the individual must exercise some influence upon its germ-cells . . . " Professor Weismann does indeed go on to say that this influence must be extremely slight, but we do not care how slight the changes produced may be, provided they exist and can be transmitted. On an earlier page (p. 101) he said in regard to variations generally that we should not expect to find them conspicuous; their frequency would be enough, if they could be accumulated. The same applies here, if stirring events that occur to the somatic cells can produce any effect at all on offspring. A very small effect, provided it can be repeated and accumulated in successive generations, is all that even the most exacting Lamarckian will ask for. Having now made the reader acquainted with the position taken by the leading Charles-Darwinian authorities, I will return to Professor Weismann himself, who declares that the transmission of acquired characters "at first sight certainly seems necessary," and that "it appears rash to attempt to dispense with its aid." He continues:-- "Many phenomena only appear to be intelligible if we assume the hereditary transmission of such acquired characters as the changes which we ascribe to the use or disuse of particula
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