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of such a combination of powerful poisons does not appear, but the percentage of deaths must have been very high, as the practice was generally condemned. Insensibility could have been produced only by swallowing large quantities of the liquid, which dripped into the nose and mouth when the sponge was applied, and a lethal quantity might thus be swallowed. The method was revived, with various modifications, from time to time, but as often fell into disuse. As late as 1782 it was sometimes attempted, and in that year the King of Poland is said to have been completely anaesthetized and to have recovered, after a painless amputation had been performed by the surgeons. Peter of Abano was one of the first great men produced by the University of Padua. His fate would have been even more tragic than that of the shipwrecked Arnald had he not cheated the purifying fagots of the church by dying opportunely on the eve of his execution for heresy. But if his spirit had cheated the fanatics, his body could not, and his bones were burned for his heresy. He had dared to deny the existence of a devil, and had suggested that the case of a patient who lay in a trance for three days might help to explain some miracles, like the raising of Lazarus. His great work was Conciliator Differentiarum, an attempt to reconcile physicians and philosophers. But his researches were not confined to medicine, for he seems to have had an inkling of the hitherto unknown fact that air possesses weight, and his calculation of the length of the year at three hundred and sixty-five days, six hours, and four minutes, is exceptionally accurate for the age in which he lived. He was probably the first of the Western writers to teach that the brain is the source of the nerves, and the heart the source of the vessels. From this it is seen that he was groping in the direction of an explanation of the circulation of the blood, as demonstrated by Harvey three centuries later. The work of Arnald and Peter of Abano in "reviving" medicine was continued actively by Mondino (1276-1326) of Bologna, the "restorer of anatomy," and by Guy of Chauliac: (born about 1300), the "restorer of surgery." All through the early Middle Ages dissections of human bodies had been forbidden, and even dissection of the lower animals gradually fell into disrepute because physicians detected in such practices were sometimes accused of sorcery. Before the close of the thirteenth century,
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