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he farmers and stock raisers of Great Britain than cattle plague or pleuropneumonia, and they are now willing and ready to put up with any restrictions, of however drastic a character, considered necessary by the central department to stamp it out." The British authorities have succeeded in suppressing each outbreak, but reinfection often occurs from the neighboring continent. At the present time (April, 1922) Great Britain is having a siege of the disease, but is applying vigorous measures for its suppression. In November, 1906, the disease reached Belgium from France, where it was quite prevalent, and by the end of the year every Province in Belgium was affected, and the Netherlands as well. Efforts to eradicate it from Belgium were unavailing. The Netherlands apparently succeeded in stamping it out for about six months, but it reappeared there. The disease is also more or less prevalent in Central Europe, Spain, and in the Balkan countries. Australia and New Zealand have remained free from it. We have less accurate information regarding Asia and Africa, but the disease is known to prevail in Japan and China and in the Philippine Islands, and it is doubtful whether any considerable part of the Orient is free from it. In South America it is reported as common in Brazil, Argentina, and Uruguay, and it probably exists in other countries. Canada and Mexico are fortunately free from the disease. _Outbreaks in the United States._--Foot-and-mouth disease has appeared in the United States on six different occasions--1870, 1880, 1884, 1902, 1908, and 1914. An extensive outbreak in 1870 was introduced by way of Canada, where the infection was brought by an importation of cattle from Scotland. It spread into the New England States and New York and appears to have been arrested within a few months. Its failure to spread more extensively and its early disappearance have been ascribed to favorable conditions, such as the movement of live stock from west to east, the limited trading at that period as compared with the present time, the restriction of traffic by winter weather, and the infrequency of travel which obtained at that time among people. About 1880 two or three lots of animals affected by this disease were brought to the United States, but there was no extension from the animals originally affected. In 1884, at Portland, Me., there was a small outbreak caused by imported cattle, and the disease spread
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