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tion in the school period are now greatly lessened by medical inspection and care of the school children. In the small epidemic of smallpox which prevailed in Boston from 1881 to 1883, there was a sharp decline in the incidence of the disease in children as soon as the school age was reached, this being due to the demand of vaccination as a condition for entrance into the schools. Many of the infectious diseases are much milder in children than in adults. This is the case in typhoid fever, malaria and yellow fever. The comparative immunity of the natives to yellow fever in regions where this prevails seems to be due to their having acquired the disease in infancy in so mild a form that it was not recognized as such. The infectious diseases are preeminently the diseases of the first third of life. After the age of forty man represents a select material. He has acquired immunity to many infections by having experienced them. Habits of life have become fixed and there is a general adjustment to environment. The only infectious disease which shows no abatement in its incidence is pneumonia, and the mortality in this increases with age. Between thirty-five and fifty-five man stands on a tolerably firm foundation regarding health; after this the age atrophies begin, the effects of previous damage begin to be apparent, and the tumor incidence increases. FOOTNOTE: [1] This was the case of a woman, by occupation a cook, whose numerous exchanges of service were accompanied by the appearance of cases of typhoid fever in the families. This became so marked that an examination was made and she was found to be a typhoid carrier and as such constantly discharging typhoid bacilli. She is now isolated. CHAPTER X INHERITANCE AS A FACTOR IN DISEASE.--THE PROCESS OF CELL MULTIPLICATION.--THE SEXUAL CELLS DIFFER FROM THE OTHER CELLS OF THE BODY.--INFECTION OF THE OVUM.--INTRA-UTERINE INFECTION.--THE PLACENTA AS A BARRIER TO INFECTION.--VARIATIONS AND MUTATIONS.--THE INHERITANCE OF SUSCEPTIBILITY TO DISEASE.--THE INFLUENCE OF ALCOHOLISM IN THE PARENTS ON THE DESCENDANTS.--THE HEREDITY OF NERVOUS DISEASES.--TRANSMISSION OF DISEASE BY THE FEMALE ONLY.--HEMOPHILIA.-- THE INHERITANCE OF MALFORMATIONS.--THE CAUSES OF MALFORMATIONS.--MATERNAL IMPRESSIONS HAVE NO INFLUENCE.--EUGENICS. The question of inheritance of disease is closely associated with the study of infection, and the general subject of heredity in its bearing on d
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