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luences due to external causes (St. Hilaire), and to use and disuse of organs (Lamarck). These influences affect the structure of the gemmaria, and as the germ-cells consist of gemmaria, like those of the rest of the organism, the possibility of the transmission of acquired new characters is self-evident. The importance of correlated growth and orthogenesis is explained on a similar basis, and the Darwinian conceptions of the independent variation of individual parts, of the exclusive dominance of utility, of the influence of the struggle for existence in regard to individual selection, and of the omnipotence of natural selection, are energetically denied. Oscar Hertwig,(68) de Vries, Driesch(69) and others attempt to reconcile the preformationist and the epigenetic standpoints, and "to extract what is good and usable out of both." Hertwig and Driesch, however, can only be mentioned with reservations in this connection. We cannot better sum up the whole tendency of the construction of mechanical theories on these last lines than in the words of Schwann: "There is within the organism no fundamental force working according to a definite idea; it arises in obedience to the blind laws of necessity." So much for the different lines followed by the mechanical theories of to-day. An idea of their general tenor can be gained from a series of much quoted general treatises, of which we must mention at least the "classics." In Wagner's "Handwoerterbuch der Physiologie," 1842, Vol. I., Lotze wrote a long introductory article to the whole work, on "Life and Vital Force." It was the challenge of the newer views to the previously vitalistic standpoint, and at the same time it was based on Lotze's general principles and interspersed with philosophical criticism of the concepts of force, cause, effect, law, &c.(70) A similar train of ideas to Lotze's is followed to-day by O. Hertwig, especially in his "Mechanismus und Biologie."(71) Lighter and more elegant was the polemic against vital force, and the outline of a mechanical theory which Du Bois-Reymond prefaced to his great work, "Untersuchungen ueber die tierische Electricitaet" (1849). It did not go nearly so deep as Lotze's essay, but perhaps for that very reason its phrases and epigrams soon became common property. We may recall how he speaks of vital force as a "general servant for everybody," of the iron atom which remains the same whether it be in the meteorite in cosmic spa
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