tive character, similar to those
used in eczema and burns.
#Dermatitis Medicamentosa.#
#What do you understand by dermatitis medicamentosa?#
Under this head are included all eruptions due to the ingestion or
absorption of certain drugs.
In rare instances one dose will have such effect; commonly, however, it
results only after several days' or weeks' continued administration.
With some drugs such effect is the rule, with others it is exceptional,
nor are all individuals equally susceptible.
#How is the eruption produced in dermatitis medicamentosa?#
In some instances it is probably due to the elimination of the drug
through the cutaneous structures; in others, to the action of the
drug upon the nervous system. The view that the drug acts as a toxin or
generates some toxin or irritant material in the blood, to which the
eruptive phenomena may be due, has also been advanced.
[Illustration: Dermatitis medicamentosa.
Bullous dermatitis from iodide of potassium.]
#What is the character of the eruption in dermatitis medicamentosa?#
It may be erythematous, papular, urticarial, vesicular, pustular or
bullous, and, if the administration of the drug is continued, even
gangrenous.
#Name the more common drugs having such action.#
Antipyrin, arsenic, atropia (or belladonna), bromides, chloral, copaiba,
cubebs, digitalis, iodides, mercury, opium (or morphia), quinine,
salicylic acid, stramonium, acetanilid, sulphonal, phenacetin,
turpentine, many of the new coal-tar derivatives, etc.
#State frequency and types of eruption due to the ingestion of antipyrin.#
Not uncommon. _Erythematous_, morbilliform and erythemato-papular;
itching is usually present and moderate desquamation may follow.
Acetanilid, sulphonal, phenacetin, and other drugs of this class may
provoke like eruptions.
#Mention frequency and types of eruption due to the ingestion of arsenic.#
Rare. Erythematous, erythemato-papular; exceptionally, herpetic, and
pigmentary. Herpes zoster has been thought to follow its use. Keratosis
of the palms and soles has also been occasionally observed, which, in
rare instances, has developed into epithelioma.
#Mention frequency and types of eruption due to the ingestion of atropia
(or belladonna).#
Not uncommon. _Erythematous_ and _scarlatinoid_; usually no febrile
disturbance, and desquamation seldom follows.
#Give frequency and types of cutaneous distur
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