medicinal substances such as the iodides and
bromides internally, and tar externally.

Working in a dusty or dirty atmosphere is often influential, resulting
in a blocking-up of the gland ducts. Workmen in paraffin oils or other
petroleum products often present a furuncle-like acne.

The disease is more common in individuals of light complexion.

#Is there any difficulty in the diagnosis of acne?#

Not if it be remembered that acne eruption is limited to certain parts
and is always follicular, and that the several stages, from the comedo
to the matured lesion, are usually to be seen in the individual case.

#In what respect does the pustular syphiloderm differ from acne?#

By its general distribution, the longer duration of the individual
lesions, the darker color, and the presence of concomitant symptoms of
syphilis.

#What is the pathology of acne?#

Primarily, acne is a folliculitis, due to retention or decomposition of
the sebaceous secretion or to the introduction of a micro-organism;
subsequently, the tissue immediately surrounding becoming involved, with
the possible destruction of the sebaceous follicle as a result. The
degree of inflammatory action determines the character of the lesions.

#State the prognosis of acne.#

It is usually an obstinate disease, but curable. Some cases yield
readily, others are exceedingly rebellious, especially acne of the back.
Success depends in a great measure upon a recognition and removal of the
predisposing condition. Treatment is ordinarily a matter of months.

#What measures of treatment are usually demanded in acne?#

Constitutional and local measures; the former when indicated, the latter
always.

#Upon what is the constitutional treatment based?#

Upon indications. Diet and hygienic measures are important.

In dyspepsia and constipation, bitter tonics, alkalies, acids, pepsin,
saline and vegetable laxatives, are variously prescribed. Special
mention may be made of the following:--

[Rx] Ext. rhamni pursh. fl., .............. f[dram]ij-f[dram]iv
Tinct. nucis vom., ................... f[dram]iij
Tinct. cardamomi comp., .......q.s. ad [Oz]iij. M.

SIG.--f[dram]t.d.

Or Hunyadi Janos or Friedrichshall water may be employed for a laxative
purpose.

In chlorotic and anaemic cases the ferruginous preparations are of
advantage. Cod-liver oil is often a remedy of great value, and is
especially useful in strumous and debilit