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ints which usually mark the lesions are probably due to accumulation of dirt, but may, as some writers maintain, be due to the presence of pigment-granules resulting from chemical change in the sebaceous matter. #Is there any difficulty in the diagnosis of comedo?# No. It can scarcely be confounded with milium, as in this latter disease the lesion has no open outlet, no black point, and the contents cannot be squeezed out. #Give the prognosis of comedo.# The result of treatment is usually favorable, although the disease is often rebellious. Relapses are not uncommon. #How would you treat a case of comedo?# By systemic (if indicated) and local measures. The constitutional treatment aims at correction or palliation of the predisposing conditions, and the external applications have in view a removal of the sebaceous plugs and stimulation of the glands and skin to healthy action. [Illustration: Fig. 9. Comedo Extractor.] #Name the systemic remedies commonly employed.# Cod-liver oil, iron, quinine, arsenic, nux vomica and other tonics; ergot in those cases in which there is lack of muscular tone, salines and aperient pills in constipation. The digestion is to be looked after and the bowels kept regular; indigestible food of all kinds is to be interdicted. Hygienic measures, such as general and local bathing, local massage, calisthenics, and open-air exercise, are of service. #Describe the local treatment.# Steaming the face or prolonged applications of hot water; washing with ordinary toilet soap and hot water, or, in sluggish cases, using tincture of green soap (tinct. saponis viridis) instead of the toilet soap; removal of the sebaceous plugs by mechanical means, such as lateral pressure with the finger ends or perpendicular pressure with a watch-key with rounded edges, or with an instrument specially contrived for this purpose; and after these preliminary measures, which should be carried out every night, a stimulating sulphur ointment or lotion, such as employed in the treatment of acne (_q. v._), is to be thoroughly applied. The following is valuable:-- [Rx] Zinci sulphatis, Potassi sulphureti, . [=a][=a] ....... [dram]j-[dram]iv. Alcoholi ............................. f[Oz]ss. Aquae, ................. q.s. ad ...... f[Oz]iv. M. Should slight scaliness or a mild degree of irritation of the skin be brought about, active external treatment is to b
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