orable to the method employed, which is as
follows:
The minimal fatal dose of a given poison was selected, and found to be in a
certain relation to the body weight.
Immediately upon the injection of the poison a solution of sodium chloride,
0.75 per cent. in strength, was injected into the subcutaneous tissues of
the neck, in quantities being eight per cent. of the body weight of the
animal.
In the case of those poisons whose effect is not instantaneous, the
injection of saline solution was made on the first appearance of toxic
symptoms. In other poisons the injection was made at once.
The result of the use of salines was a diuresis varying in the promptness
of its appearance and in its amount.
Those animals in which diuresis was limited at first and then increased
generally recovered, while those in which diuresis was not established
perished. The poison used was found in the urine of those which died and
also those which recovered.
The author succeeded in rescuing animals poisoned by alcohol, strychnine,
chloral, and aconitine. With morphine, curare, and hypnone, the method of
elimination failed, although ten per cent. in quantity of the body weight
of the animal was used in the saline injection. With aconitine, diuresis
was not always established, and when it failed the animal died in
convulsions.--_Centralblatt fur die Medicinischen Wissenschaften, December_
18, 1886.
* * * * *
A catalogue, containing brief notices of many important scientific papers
heretofore published in the SUPPLEMENT, may be had gratis at this office.
* * * * *
THE SCIENTIFIC AMERICAN SUPPLEMENT.
PUBLISHED WEEKLY.
Terms of Subscription, $5 a Year.
Sent by mail, postage prepaid, to subscribers in any part of the United
States or Canada. Six dollars a year, sent, prepaid, to any foreign
country.
All the back numbers of THE SUPPLEMENT, from the commencement, January 1,
1876, can be had. Price, 10 cents each.
All the back volumes of THE SUPPLEMENT can likewise be supplied. Two
volumes are issued yearly. Price of each volume, $2.50, stitched in paper,
or $3.50, bound in stiff covers.
COMBINED RATES--One copy of SCIENTIFIC AMERICAN and one copy of SCIENTIFIC
AMERICAN SUPPLEMENT, one year, postpaid, $7.00.
A liberal discount to booksellers, news agents, and canvassers.
MUNN & CO., Publishers,
361 Broadway, New York, N.Y.
*
|