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l parts, as head, liver, spleen, mesaraic veins, heart, womb, stomach, &c., and most especially from distemperature of spirits (which, as [2543]Hercules de Saxonia contends, are wholly immaterial), or from the four humours in those seats, whether they be hot or cold, natural, unnatural, innate or adventitious, intended or remitted, simple or mixed, their diverse mixtures, and several adustions, combinations, which may be as diversely varied, as those [2544]four first qualities in [2545] Clavius, and produce as many several symptoms and monstrous fictions as wine doth effect, which as Andreas Bachius observes, _lib. 3. de vino, cap. 20._ are infinite. Of greater note be these. If it be natural melancholy, as Lod. Mercatus, _lib. 1. cap. 17. de melan._ T. Bright. _c. 16._ hath largely described, either of the spleen, or of the veins, faulty by excess of quantity, or thickness of substance, it is a cold and dry humour, as Montanus affirms, _consil. 26_ the parties are sad, timorous and fearful. Prosper Calenus, in his book _de atra bile_, will have them to be more stupid than ordinary, cold, heavy, solitary, sluggish. _Si multam atram bilem et frigidam habent_. Hercules de Saxonia, _c. 19. l. 7._ [2546]"holds these that are naturally melancholy, to be of a leaden colour or black," and so doth Guianerius, _c. 3. tract. 15._ and such as think themselves dead many times, or that they see, talk with black men, dead men, spirits and goblins frequently, if it be in excess. These symptoms vary according to the mixture of those four humours adust, which is unnatural melancholy. For as Trallianus hath written, _cap. 16. l. 7._ [2547]"There is not one cause of this melancholy, nor one humour which begets, but divers diversely intermixed, from whence proceeds this variety of symptoms:" and those varying again as they are hot or cold. [2548]"Cold melancholy" (saith Benedic. Vittorius Faventinus _pract. mag._) "is a cause of dotage, and more mild symptoms, if hot or more adust, of more violent passions, and furies." Fracastorius, _l. 2. de intellect._ will have us to consider well of it, [2549]"with what kind of melancholy every one is troubled, for it much avails to know it; one is enraged by fervent heat, another is possessed by sad and cold; one is fearful, shamefaced; the other impudent and bold;" as Ajax, _Arma rapit superosque furens inpraelia poscit_: quite mad or tending to madness. _Nunc hos, nunc impetit illos._ Bellerophon on
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