ics, for it soaks
through the gall-ducts, and is frequently found in the cellular membrane.
This kind of jaundice is not generally attended with pain, neither at the
extremity of the bile-duct, where it enters the duodenum, nor on the region
of the gall-bladder.

Mr. S. a gentleman between 40 and 50 years of age, had had the jaundice
about six weeks, without pain, sickness, or fever; and had taken emetics,
cathartics, mercurials, bitters, chalybeates, essential oil, and ether,
without apparent advantage. On a supposition that the obstruction of the
bile might be owing to the paralysis, or torpid action of the common
bile-duct, and the stimulants taken into the stomach seeming to have no
effect, I directed half a score smart electric shocks from a coated bottle,
which held about a quart, to be passed through the liver, and along the
course of the common gall-duct, as near as could be guessed, and on that
very day the stools became yellow; he continued the electric shocks a few
days more, and his skin gradually became clear.

3. The bilious vomiting and purging, that affects some people by intervals
of a few weeks, is a less degree of this disease; the bile-duct is less
irritable than natural, and hence the bile becomes accumulated in the
gall-bladder, and hepatic ducts, till by its quantity, acrimony or
viscidity, a greater degree of irritation is produced, and it is suddenly
evacuated, or lastly from the absorption of the more liquid parts of the
bile, the remainder becomes inspissated, and chrystallizes into masses too
large to pass, and forms another kind of jaundice, where the bile-duct is
not quite paralytic, or has regained its irritability.

This disease is attended with much pain, which at first is felt at the pit
of the stomach, exactly in the centre of the body, where the bile-duct
enters the duodenum; afterwards, when the size of the bile-stones increase,
it is also felt on the right side, where the gall-bladder is situated. The
former pain at the pit of the stomach recurs by intervals, as the
bile-stone is pushed against the neck of the duct; like the paroxysms of
the stone in the urinary bladder, the other is a more dull and constant
pain.

Where these bile-stones are too large to pass, and the bile-ducts possess
their sensibility, this becomes a very painful and hopeless disease. I made
the following experiments with a view to their chemical solution.

Some fragments of the same bile-stone were put into